Related references
Note: Only part of the references are listed.Mre11 and Exo1 contribute to the initiation and processivity of resection at meiotic double-strand breaks made independently of Spo11
Adam Hodgson et al.
DNA REPAIR (2011)
Mre11 Nuclease Activity and Ctp1 Regulate Chk1 Activation by Rad3ATR and Tel1ATM Checkpoint Kinases at Double-Strand Breaks
Oliver Limbo et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Making the best of the loose ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection
Tanya T. Paull
DNA REPAIR (2010)
Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2
Eleni P. Mimitou et al.
EMBO JOURNAL (2010)
Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
Eun Yong Shim et al.
EMBO JOURNAL (2010)
Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae
Hengyao Niu et al.
NATURE (2010)
DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2
Petr Cejka et al.
NATURE (2010)
Mre11-Rad50-Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks
Matthew L. Nicolette et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Physical Interaction between Replication Protein A (RPA) and MRN: Involvement of RPA2 Phosphorylation and the N-Terminus of RPA1
Greg G. Oakley et al.
BIOCHEMISTRY (2009)
Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae
Brian M. Wasko et al.
DNA REPAIR (2009)
DNA end resection: Many nucleases make light work
Eleni P. Mimitou et al.
DNA REPAIR (2009)
Meiotic DNA Double-Strand Break Repair Requires Two Nucleases, MRN and Ctp1, To Produce a Single Size Class of Rec12 (Spo11)-Oligonucleotide Complexes
Neta Milman et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Ctp1CtIP and Rad32Mre11 Nuclease Activity Are Required for Rec12Spo11 Removal, but Rec12Spo11 Removal Is Dispensable for Other MRN-Dependent Meiotic Functions
Edgar Hartsuiker et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
CUP Links DNA Double-Strand Break Sensing to Resection
Zhongsheng You et al.
MOLECULAR CELL (2009)
Distinct Requirements for the Rad32Mre11 Nuclease and Ctp1CtIP in the Removal of Covalently Bound Topoisomerase I and II from DNA
Edgar Hartsuiker et al.
MOLECULAR CELL (2009)
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
Maximina H. Yun et al.
NATURE (2009)
Ctp1 and Exonuclease 1, alternative nucleases regulated by the MRN complex, are required for efficient meiotic recombination
Joseph A. Farah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Ctp1 and the MRN-Complex Are Required for Endonucleolytic Rec12 Removal with Release of a Single Class of Oligonucleotides in Fission Yeast
Maja Rothenberg et al.
PLOS GENETICS (2009)
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair
R. Scott Williams et al.
CELL (2008)
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
Zhu Zhu et al.
CELL (2008)
Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation
Jeffrey Buis et al.
CELL (2008)
Break dosage, cell cycle stage and DNA replication influence DNA double strand break response
Christian Zierhut et al.
EMBO JOURNAL (2008)
Mus81 is essential for sister chromatid recombination at broken replication forks
Laura Roseaulin et al.
EMBO JOURNAL (2008)
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
Serge Gravel et al.
GENES & DEVELOPMENT (2008)
Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae
Dongliang Wu et al.
GENETICS (2008)
Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 coraplex
Yufuko Akamatsu et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
Eleni P. Mimitou et al.
NATURE (2008)
Genome instability: a mechanistic view of its causes and consequences
Andres Aguilera et al.
NATURE REVIEWS GENETICS (2008)
Sae2 is an endonuclease that processes hairpin DNA cooperatively with the Mre11/Rad50/Xrs2 complex
Bettina M. Lengsfeld et al.
MOLECULAR CELL (2007)
Human CtIP promotes DNA end resection
Alessandro A. Sartori et al.
NATURE (2007)
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
Oliver Limbo et al.
MOLECULAR CELL (2007)
The mre11 complex mediates the S-Phase checkpoint through an interaction with replication protein A
Erin Olson et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination
Yu Zhang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Xlf1 is required for DNA repair by nonhomologous end joining in Schizosaccharomyces pombe
Santiago Cavero et al.
GENETICS (2007)
BRCA1 ubiquitinates its phosphorylation-dependent binding partners CtIP
Xiaochun Yu et al.
GENES & DEVELOPMENT (2006)
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
Li-Lin Du et al.
GENES & DEVELOPMENT (2006)
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling
M Clerici et al.
EMBO REPORTS (2006)
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
A Jazayeri et al.
NATURE CELL BIOLOGY (2006)
Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
RA Greenberg et al.
GENES & DEVELOPMENT (2006)
Mutations of the Yku80 C terminus and Xrs2 FHA domain specifically block yeast nonhomologous end joining
PL Palmbos et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Mutations in Mre11 phosphoesterase motif I that impair Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex stability in addition to nuclease activity
BO Krogh et al.
GENETICS (2005)
The Mre11/Rad50/Xrs2 complex and non-homologous end-joining of incompatible ends in S.cerevisiae
XM Zhang et al.
DNA REPAIR (2005)
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends
M Clerici et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks
MJ Neale et al.
NATURE (2005)
New insights into NHEJ repair processes in prokaryotes
RS Pitcher et al.
CELL CYCLE (2005)
Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis haploid insufficiency
PL Chen et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Effect of meiotic recombination on the production of aneuploid gametes in humans
NE Lamb et al.
CYTOGENETIC AND GENOME RESEARCH (2005)
RNase-sensitive DNA modification(s) initiates S. pombe mating-type switching
S Vengrova et al.
GENES & DEVELOPMENT (2004)
Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells
LK Lewis et al.
GENETICS (2004)
Replication protein A and the Mre11•Rad50•Nbs1 complex co-localize and interact at sites of stalled replication forks
JG Robison et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
An overview of three new disorders associated with genetic instability: LIG4 syndrome, RS-SCID and ATR-Seckel syndrome
M O'Driscoll et al.
DNA REPAIR (2004)
A programmed strand-specific and modified nick in S-pombe constitutes a novel type of chromosomal imprint
A Kaykov et al.
CURRENT BIOLOGY (2004)
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
XC Yu et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
The Mre11 nuclease is not required for 5′ to 3′ resection at multiple HO-induced double-strand breaks
B Llorente et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
DNA damage checkpoint and repair centers
M Lisby et al.
CURRENT OPINION IN CELL BIOLOGY (2004)
Retention but not recruitment of Crb2 at double-strand breaks requires Rad1 and Rad3 complexes
LL Du et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint
C Chahwan et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres
K Tomita et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
Repair of DNA double strand breaks by non-homologous end joining
SP Lees-Miller et al.
BIOCHIMIE (2003)
Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification
MJ Difilippantonio et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
D D'Amours et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions
NE Sharpless et al.
MOLECULAR CELL (2001)
Recombination at double-strand breaks and DNA ends: Conserved mechanisms from phage to humans
GA Cromie et al.
MOLECULAR CELL (2001)
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdfl/Hdf2 complexes
L Chen et al.
MOLECULAR CELL (2001)
Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast
A Lopez-Girona et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Homologous DNA recombination in vertebrate cells
E Sonoda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Stopped-flow kinetic analysis of replication protein A-binding DNA -: Damage recognition and affinity for single-stranded DNA reveal differential contributions of kon and koff rate constants
SM Patrick et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Genome maintenance mechanisms for preventing cancer
JHJ Hoeijmakers
NATURE (2001)
Protection of telomeres by the Ku protein in fission yeast
P Baumann et al.
MOLECULAR BIOLOGY OF THE CELL (2000)