Journal
NANOMATERIALS
Volume 6, Issue 1, Pages -Publisher
MDPI
DOI: 10.3390/nano6010005
Keywords
biosensor; bimetallic; nanoparticle; electrocatalytic; catalytic
Categories
Funding
- Ministry of Science and Technology (MOST) [103-2221-E-011-156-MY3, 103-3113-E-011-001]
- Top University Projects of the Ministry of Education (MOE) [100H451401]
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This article presents a review of electrochemical bio-sensing for target analytes based on the use of electrocatalytic bimetallic nanoparticles (NPs), which can improve both the sensitivity and selectivity of biosensors. The review moves quickly from an introduction to the field of bio-sensing, to the importance of biosensors in today's society, the nature of the electrochemical methods employed and the attendant problems encountered. The role of electrocatalysts is introduced with reference to the three generations of biosensors. The contributions made by previous workers using bimetallic constructs, grouped by target analyte, are then examined in detail; following which, the synthesis and characterization of the catalytic particles is examined prior to a summary of the current state of endeavor. Finally, some perspectives for the future of bimetallic NPs in biosensors are given.
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