Related references
Note: Only part of the references are listed.Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death
Gang Cheng et al.
CANCER RESEARCH (2012)
Small-Molecule Inhibition of BRDT for Male Contraception
Martin M. Matzuk et al.
CELL (2012)
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
Zuqin Nie et al.
CELL (2012)
Transcriptional Amplification in Tumor Cells with Elevated c-Myc
Charles Y. Lin et al.
CELL (2012)
p53-induced Gene 3 Mediates Cell Death Induced by Glutathione Peroxidase 3
Hui Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials
Peter M. Rothwell et al.
LANCET (2012)
MDM4 is a key therapeutic target in cutaneous melanoma
Agnieszka Gembarska et al.
NATURE MEDICINE (2012)
Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop
Nicola Aceto et al.
NATURE MEDICINE (2012)
CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer
Qiqun Zeng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression
Zhao-Qiu Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Functional genomics identifies therapeutic targets for MYC-driven cancer
Masafumi Toyoshima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis
Jessica D. Kessler et al.
SCIENCE (2012)
Use and Abuse of RNAi to Study Mammalian Gene Function
William G. Kaelin
SCIENCE (2012)
Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
Dimitrios Iliopoulos et al.
CANCER RESEARCH (2011)
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Jake E. Delmore et al.
CELL (2011)
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Johannes Zuber et al.
NATURE (2011)
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
Gina M. De Nicola et al.
NATURE (2011)
被撤回的出版物: Selective killing of cancer cells by a small molecule targeting the stress response to ROS (Retracted article. See vol. 561, pg. 420, 2018)
Lakshmi Raj et al.
NATURE (2011)
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
Alice T. Shaw et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The N-Terminal Integrity Is Critical for the Stability and Biological Functions of Endostatint
Yan Fu et al.
BIOCHEMISTRY (2010)
Cell Signaling by Receptor Tyrosine Kinases
Mark A. Lemmon et al.
CELL (2010)
Selective inhibition of BET bromodomains
Panagis Filippakopoulos et al.
NATURE (2010)
Redox-Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities
Georg T. Wondrak
ANTIOXIDANTS & REDOX SIGNALING (2009)
Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission
Heather A. Hirsch et al.
CANCER RESEARCH (2009)
Tumor suppressors and cell metabolism: a recipe for cancer growth
Russell G. Jones et al.
GENES & DEVELOPMENT (2009)
Association of reactive oxygen species levels and radioresistance in cancer stem cells
Maximilian Diehn et al.
NATURE (2009)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
KangAe Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Cancer cell killing via ROS To increase or decrease, that is the question
Jie Wang et al.
CANCER BIOLOGY & THERAPY (2008)
Autocrine IL-6 signaling: A key event in tumorigenesis?
Sergei Grivennikov et al.
CANCER CELL (2008)
ROS and p53: A versatile partnership
Bin Liu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Role of reactive oxygen species-mediated mitochondrial dysregulation in 3-bromopyruvate induced cell death in hepatoma cells
Ji Su Kim et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2008)
Adaptive response to GSH depletion and resistance to L-buthionine-(S,R)-sulfoximine: involvement of Nrf2 activation
Hyang-Rim Lee et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)
Elesclomol induces cancer cell apoptosis through oxidative stress
Jessica R. Kirshner et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Modelling Myc inhibition as a cancer therapy
Laura Soucek et al.
NATURE (2008)
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Sian Jones et al.
SCIENCE (2008)
Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest
Wan Seok Yang et al.
GENOME BIOLOGY (2008)
Evaluation of HIF-1 inhibitors as anticancer agents
Gregg L. Semenza
DRUG DISCOVERY TODAY (2007)
Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide
Jun Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC
Andrei Goga et al.
NATURE MEDICINE (2007)
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention - Systematic review and meta-analysis
Goran Bjelakovic et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo
Jerome Alexandre et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Oxidative stress and apoptosis: a new treatment paradigm in cancer
RH Engel et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2006)
Resistance to paclitaxel is proportional to cellular total antioxidant capacity
B Ramanathan et al.
CANCER RESEARCH (2005)
Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
YH Ko et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)