Journal
MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL
Volume 17, Issue 6, Pages E943-E947Publisher
MEDICINA ORAL S L
DOI: 10.4317/medoral.17778
Keywords
Oral lichen planus; clinical features; malignant transformation; oral cancer
Categories
Funding
- Science and Technology Commission of Shanghai [08DZ2271100, 10DZ1974200, 11DZ1972600]
- Shanghai Leading Academic Discipline Project [S30206]
Ask authors/readers for more resources
Objective: To investigate the epidemiological and clinical characteristics of a relatively large cohort of patients with oral lichen planus (OLP) from eastern China. Study design: A total of 518 patients with histologically confirmed OLP in a long-term follow-up period (6 months-21.5 years) were retrospectively reviewed in our clinic. Results: Of the 518 patients, 353 females and 165 males were identified. The average age at diagnosis was 46.3 years (range 9-81 years) with the buccal mucosa being the most common site (87.8%). At initial presentation, white lichen and red lichen was seen in 52.3% and 47.7% patients, respectively. Of these, 5 (0.96%) patients previously diagnosed clinically and histopathologically as OLP developed oral cancer. All of them were the females with no a history of smoking or alcohol use. Conclusions: Clinical features of eastern Chinese OLP patients were elucidated. Notably, approximately 1% of OLP developed into cancer, which provides further evidence of potentially malignant nature of OLP.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available