4.3 Article

In vivo efficacy of biocompatible silver nanoparticles cream for empirical wound healing

Journal

JOURNAL OF TISSUE VIABILITY
Volume 27, Issue 4, Pages 257-261

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.jtv.2018.08.007

Keywords

Nanotechnology; Silver nanoparticles; Biocompatibility; In vivo wound healing

Funding

  1. Science & Engineering Research Board 'SERB' - 'India' [PDF/2016/003910]
  2. Rajiv Gandhi University of Health Sciences 'RGUHS', Bengaluru - 'India' [P007/2016-17]

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Wound healing is a complicated process that begins at the onset of injury and a continued process till complete healing. The emergence of nanotechnology has provided a new therapeutic modality to silver nanoparticles in treatment of wounds. However, the safety of these silver nanoparticles in the process of wound healing is yet to be elucidated; nevertheless, biocompatibility is the primary concern. Biosynthesis of silver nanoparticles was synthesized using aqueous clove extract and silver nitrate solution under microwave and the obtained particles size were 30-60 nm and roughly spherical in shape. The present study focused on the efficacy of biocompatible silver nanoparticles in vivo wound healing process. Consequently, this study supported the incorporation of biosynthesized silver nanoparticles in wound dressings as a cream formulation for improved healthcare.

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