Journal
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
Volume 10, Issue 6, Pages 910-913Publisher
OXFORD UNIV PRESS
DOI: 10.1510/icvts.2010.235127
Keywords
Perioperative bleeding; Hemostasis; Hemostatic agent; Fibrin sealants
Ask authors/readers for more resources
Fibrin glue products and collagen patches are frequently used as a sealing product, preventing surgical side bleedings. This is especially true in the field of cardiovascular surgery, where increasing numbers of patients are being operated with antiplatelet and anticoagulation therapy. The aim of this report was, in an in vitro hemodynamic setting, to examine the sealant properties of the TachoSil (R) (Nycomed Pharma, Linz, Austria) patch. Burst pressure and normal force of 15 TachoSil (R) sealed defects were measured. This was determined in a closed hydraulic system. Mean burst pressure load for a 5-mm defect was 69 +/- 11.4 mmHg; for a 7-mm defect was 63 +/- 16 mmHg; and, 62 +/- 16 mmHg for the defect with a diameter of 10 mm (P>0.05). The mean calculated normal force was as follows: 0.91 +/- 0.15 N for the 5 mm defect, 6.5 +/- 1.6 N for the 7 mm, and 8.1 +/- 0.75 N for the 10 mm defect. The TachoSil (R) patch has the capability to seal small defects. However, at the larger defects the seal character was significantly reduced. These results suggest that the device may be a good alternative for hemostasis for small defects. The capacity to curtail or stop hemorrhage at the larger defects is unlikely. (C) 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available