Journal
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY
Volume 10, Issue 3, Pages 428-433Publisher
OXFORD UNIV PRESS
DOI: 10.1510/icvts.2009.218594
Keywords
Univentricular heart; Fontan circulation; Cavopulmonary connection; Cardiac output
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In a Fontan circuit the mechanisms involved in control of cardiac output at rest and during exercise differ significantly from normal. The classical model presumes an unlimited preload which is not available in the Fontan circuit. This review critically analyses the role of contractility, heart rate, and afterload and highlights the importance of pulmonary vascular resistance (PVR) in determining adequate preload and, therefore, cardiac output in these patients. A conceptual model of the determinants of cardiac output in Fontan patients is presented. (c) 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.
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