4.2 Review

Sleep-dependent memory processing

Journal

HARVARD REVIEW OF PSYCHIATRY
Volume 16, Issue 5, Pages 287-298

Publisher

INFORMA HEALTHCARE
DOI: 10.1080/10673220802432517

Keywords

consolidation; declarative; encoding; learning; memory; neuroimaging; NREM; plasticity; procedural; REM; sleep

Categories

Funding

  1. NIMH NIH HHS [MH069935, MH65292, MH48832, MH67754] Funding Source: Medline
  2. NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH065292, R03MH069935, R21MH067754] Funding Source: NIH RePORTER

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While the functions of sleep remain largely unknown, one exciting hypothesis is that sleep contributes importantly to processes of memory and brain plasticity. Over the last decade, a large body of work has provided substantive evidence supporting this role of sleep in what is becoming known as sleep-dependent memory processing. This review offers a summary of these data, focusing specifically on the role of sleep in (1) memory encoding, (2) memory consolidation (along with the brain basis of this process), and (3) neural plasticity. The clinical ramifications of such findings are also explored.

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