Journal
CURRENT OPINION IN VIROLOGY
Volume 7, Issue -, Pages 79-87Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2014.05.005
Keywords
-
Categories
Funding
- NIH [R01GM085448, P41GM103694, R24GM098791, HHSN272201400006C, U54GM62116]
Ask authors/readers for more resources
While all viruses must transit the plasma membrane of mammalian cells to initiate infection, we know little about the complex processes involved in viral attachment, which commonly involve recognition of glycans by viral proteins. Glycan microarrays derived from both synthetic glycans and natural glycans isolated through shotgun glycomics approaches provide novel platforms for interrogating diverse glycans as potential viral receptors. Recent studies with influenza and rotaviruses using such glycan microarrays provide examples of their utility in exploring the challenging questions raised in efforts to define the complex mechanistic protein-glycan interactions that regulate virus attachment to host cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available