Journal
CURRENT OPINION IN VIROLOGY
Volume 4, Issue -, Pages 8-14Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2013.10.002
Keywords
-
Categories
Funding
- Ambizione [PZ00P3_131988]
- Swiss National Foundation InfectX [232974]
- ERC [232974]
- European Research Council (ERC) [232974] Funding Source: European Research Council (ERC)
- Swiss National Science Foundation (SNF) [PZ00P3_131988] Funding Source: Swiss National Science Foundation (SNF)
Ask authors/readers for more resources
As obligate intracellular parasites viruses rely on host cell factors and functions for all stages of infection, from entry to spread. Characterization of these cellular components is critical to advance our understanding of the infection process and develop novel means to combat viral pathogens. To this end, the recent application of next generation approaches including compound screening, cell-targeting RNA interference, gene knockouts, and several proteomics approaches has served to expand our understanding of virus-host interactions, and facilitated the discovery of potential antiviral targets. Here we review recent progress in the use of these next generation approaches and discuss their challenges, pitfalls, and potential applications for the study of virus-host interplay.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available