Journal
CURRENT OPINION IN VIROLOGY
Volume 3, Issue 3, Pages 238-244Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2013.05.012
Keywords
-
Categories
Funding
- NIH [CA019014, CA163217, CA096500]
Ask authors/readers for more resources
Kaposi sarcoma-associated herpesvirus (KSHV) is the etiological agent of several human malignancies. The virus is able to modulate pro-proliferative pathways to its advantage, while simultaneously inhibiting pro-apoptotic signaling pathways. These functions are carried out by multiple viral proteins acting in concert. The overall outcome is the survival and proliferation of the infected cell. Additionally, the virus also modulates innate immune pathways to allow for prolonged survival of the infected cell following primary infection, and during viral latency. Here we review the latest advances in our knowledge of KSHV pathogenesis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available