4.5 Article

An animal model that reflects human disease: the common marmoset (Callithrix jacchus)

Journal

CURRENT OPINION IN VIROLOGY
Volume 2, Issue 3, Pages 357-362

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.coviro.2012.02.007

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Funding

  1. NIH laboratory construction grant [C06 RR12087]
  2. Southwest National Primate Research Center base grant [P51 482RR013986]

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The common marmoset is a new world primate belonging to the Callitrichidae family weighing between 350 and 400 g. The marmoset has been shown to be an outstanding model for studying aging, reproduction, neuroscience, toxicology, and infectious disease. With regard to their susceptibility to infectious agents, they are exquisite NHP models for viral, protozoan and bacterial agents, as well as prions. The marmoset provides the advantages of a small animal model in high containment coupled with the immunological repertoire of a nonhuman primate and susceptibility to wild type, non-adapted viruses.

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