4.1 Article

Genetic Basis of MPN: Beyond JAK2-V617F

Related references

Note: Only part of the references are listed.
Article Immunology

MPN patients harbor recurrent truncating mutations in transcription factor NF-E2

Jonas S. Jutzi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2013)

Article Hematology

Frequent deletions of JARID2 in leukemic transformation of chronic myeloid malignancies

Ana Puda et al.

AMERICAN JOURNAL OF HEMATOLOGY (2012)

Article Hematology

Clinical significance of genetic aberrations in secondary acute myeloid leukemia

Jelena D. Milosevic et al.

AMERICAN JOURNAL OF HEMATOLOGY (2012)

Article Genetics & Heredity

Age-Related Somatic Structural Changes in the Nuclear Genome of Human Blood Cells

Lars A. Forsberg et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2012)

Article Genetics & Heredity

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

Lambert Busque et al.

NATURE GENETICS (2012)

Article Genetics & Heredity

Detectable clonal mosaicism and its relationship to aging and cancer

Kevin B. Jacobs et al.

NATURE GENETICS (2012)

Article Genetics & Heredity

Detectable clonal mosaicism from birth to old age and its relationship to cancer

Cathy C. Laurie et al.

NATURE GENETICS (2012)

Article Biochemistry & Molecular Biology

CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage

Charles Vadnais et al.

NUCLEIC ACIDS RESEARCH (2012)

Review Genetics & Heredity

The p53 network: cellular and systemic DNA damage responses in aging and cancer

H. Christian Reinhardt et al.

TRENDS IN GENETICS (2012)

Review Oncology

The role of mutations in epigenetic regulators in myeloid malignancies

Alan H. Shih et al.

NATURE REVIEWS CANCER (2012)

Article Cell Biology

Mouse models of myeloproliferative neoplasms: JAK of all grades

Juan Li et al.

DISEASE MODELS & MECHANISMS (2011)

Review Oncology

Hydroxycarbamide: a user's guide for chronic myeloproliferative disorders

Jerry L. Spivak et al.

EXPERT REVIEW OF ANTICANCER THERAPY (2011)

Article Hematology

Deep sequencing reveals double mutations in cis of MPL exon 10 in myelloproliferative neoplasm's

Daniela Pietra et al.

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2011)

Review Neurosciences

Regulation of erythropoietin production

Wolfgang Jelkmann

JOURNAL OF PHYSIOLOGY-LONDON (2011)

Letter Oncology

DNMT3A mutations in myeloproliferative neoplasms

F. Stegelmann et al.

LEUKEMIA (2011)

Article Multidisciplinary Sciences

Frequent pathway mutations of splicing machinery in myelodysplasia

Kenichi Yoshida et al.

NATURE (2011)

Review Multidisciplinary Sciences

The Polycomb complex PRC2 and its mark in life

Raphael Margueron et al.

NATURE (2011)

Letter Medicine, General & Internal

p53 Lesions in Leukemic Transformation

Ashot Harutyunyan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Hematology

Ubiquitination and degradation of the thrombopoietin receptor c-Mpl

Sebastian J. Saur et al.

BLOOD (2010)

Review Cell & Tissue Engineering

Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer

Martin Sauvageau et al.

CELL STEM CELL (2010)

Review Immunology

Stem cells and the aging hematopoietic system

Isabel Beerman et al.

CURRENT OPINION IN IMMUNOLOGY (2010)

Article Multidisciplinary Sciences

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

Myunggon Ko et al.

NATURE (2010)

Letter Medicine, General & Internal

Somatic Mutations of IDH1 and IDH2 in the Leukemic Transformation of Myeloproliferative Neoplasms

Anthony Green et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Letter Medicine, General & Internal

LNK Mutations in JAK2 Mutation-Negative Erythrocytosis.

Terra L. Lasho et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Medicine, General & Internal

DNMT3A Mutations in Acute Myeloid Leukemia.

Timothy J. Ley et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Multidisciplinary Sciences

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

Isabel Beerman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

Mark A. Dawson et al.

NATURE (2009)

Article Oncology

Molecular and Genetic Bases of Myeloproliferative Disorders: Questions and Perspectives

Isabelle Plo et al.

CLINICAL LYMPHOMA & MYELOMA (2009)

Article Biochemistry & Molecular Biology

Isolation and characterization of a novel H1.2 complex that acts as a repressor of p53-mediated transcription

Kyunghwan Kim et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes

Mary Truscott et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Review Oncology

Genetic complexity of myeloproliferative neoplasms

R. Kralovics

LEUKEMIA (2008)

Review Biochemistry & Molecular Biology

Hematopoietic cytokine receptor signaling

S. J. Baker et al.

ONCOGENE (2007)

Article Medicine, General & Internal

JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis

Linda M. Scott et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Hematology

Polycythemia vera is not initiated by JAK2(V17F) mutation

Roberto H. Nussenzveig et al.

EXPERIMENTAL HEMATOLOGY (2007)

Article Biochemistry & Molecular Biology

Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor

Yang-Sook Cho et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation

XH Lu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Cell Biology

The Cbl interactome and its functions

MHH Schmidt et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Review Oncology

ETV6: A versatile player in leukemogenesis

SK Bohlander

SEMINARS IN CANCER BIOLOGY (2005)

Article Medicine, General & Internal

A gain-of-function mutation of JAK2 in myeloproliferative disorders

R Kralovics et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Medicine, General & Internal

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

EJ Baxter et al.

LANCET (2005)

Article Immunology

Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis

W Tong et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Article Cell Biology

Thrombopoietin signalling in physiology and disease

B Fishley et al.

GROWTH FACTORS (2004)

Article Biochemistry & Molecular Biology

Preferential methylation of unmethylated DNA by mammalian de novo DNA methyltransferase Dnmt3a

T Yokochi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Review Immunology

Haematopoietic cell-fate decisions, chromatin regulation and ikaros

K Georgopoulos

NATURE REVIEWS IMMUNOLOGY (2002)