Journal
CHEMPLUSCHEM
Volume 80, Issue 3, Pages 485-489Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cplu.201402307
Keywords
cytotoxicity; endoplasmic reticulum; fluorescent probes; naphthalenediimide; sensors
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Funding
- DAE-BRNS, Mumbai, India [37(2)/14/08/2014-BRNS]
- CSIR, New Delhi, Govt. of India for senior research fellowship
- Science and Engineering Research Board (SERB), India [SR/FT/LS-11/2011]
- Australian Research Council under a Future Fellowship scheme [FT110100152]
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An amino-core-substituted naphthalenediimide (NDI) derivative has been synthesized in good yield in two steps. The NDI bearing a diamine moiety undergoes a reversible protonation-deprotonation process, which results in intensity changes in the absorption and emission spectra. This derivative exhibits good photostability, good selectivity, high sensitivity, and is employed to exhibit the pH within the rough endoplasmic reticulum of living cells.
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