Journal
CARDIORENAL MEDICINE
Volume 2, Issue 4, Pages 314-327Publisher
KARGER
DOI: 10.1159/000343803
Keywords
Obesity; Cardiorenal metabolic syndrome; Cardiovascular disease; Kidney
Funding
- NIH [R01 HL73101-01A1, R01 HL107910-01]
- Veterans Affairs Merit System [0019]
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The prevalence of obesity has increased rapidly in the United States. Obesity affects about one third of the adult population and, even though it is attributed to excess calorie intake and inadequate physical activity, its etiopathogenesis is much more complex and is an area of active study. Lifestyle modifications (with a focus on increased activity and decreased calorie intake) have modest efficacy in the treatment of obesity. There is a dearth of safe and effective therapeutic modalities to treat obesity. In this review, we discuss the role of different treatment options in the management of obesity and its comorbidities, with a focus on recently approved drugs and the emerging role of bariatric surgery. Copyright (C) 2012 S. Karger AG, Basel
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