Journal
ALZHEIMERS RESEARCH & THERAPY
Volume 2, Issue 4, Pages -Publisher
BMC
DOI: 10.1186/alzrt47
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Funding
- Robert H. Smith Family Foundation Research Fellowship
- National Institute on Aging [AG11378, P50-AG16574, U01 AG024904-01]
- Mayo Foundation
- NATIONAL INSTITUTE ON AGING [R01AG011378] Funding Source: NIH RePORTER
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Atrophy measured on structural magnetic resonance imaging (sMRI) is a powerful biomarker of the stage and intensity of the neurodegenerative aspect of Alzheimer's disease (AD) pathology. In this review, we will discuss the role of sMRI as an AD biomarker by summarizing (a) the most commonly used methods to extract information from sMRI images, (b) the different roles in which sMRI can be used as an AD biomarker, and (c) comparisons of sMRI with other major AD biomarkers.
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