Journal
ADVANCED HEALTHCARE MATERIALS
Volume 3, Issue 2, Pages 160-175Publisher
WILEY
DOI: 10.1002/adhm.201300141
Keywords
cancer imaging; cancer therapy; drug delivery; iron oxide nanoparticles; multifunctional nanoparticles; polymeric coating
Funding
- Research Executive Agency (REA) of the European Union [PITN-GA-2010-264772]
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In the past decades, magnetic nanoparticles (MNPs) have been used in wide range of diverse applications, ranging from separation to sensing. Here, synthesis and applications of functionalized MNPs in the biomedical field are discussed, in particular in drug delivery, imaging, and cancer therapy, highlighting also recent progresses in the development of multifunctional and stimuli-responsive MNPs. The role of their size, composition, and surface functionalization is analyzed, together with their biocompatibility issues.
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