3.9 Article

Complete genome sequence of Brachyspira murdochii type strain (56-150(T))

Journal

STANDARDS IN GENOMIC SCIENCES
Volume 2, Issue 3, Pages 260-269

Publisher

BIOMED CENTRAL LTD
DOI: 10.4056/sigs.831993

Keywords

host-associated; non-pathogenic; motile; anaerobic; Gram-negative; Brachyspiraceae; Spirochaetes; GEBA

Funding

  1. US Department of Energy Office of Science
  2. University of California, Lawrence Berkeley National Laboratory [DE-AC02-05CH11231]
  3. Lawrence Livermore National Laboratory [DE-AC52-07NA27344]
  4. Los Alamos National Laboratory [DE-AC02-06NA25396]
  5. UT-Battelle
  6. Oak Ridge National Laboratory [DE-AC05-00OR22725]
  7. German Research Foundation (DFG) [INST 599/1-1, SI 1352/1-2]

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Brachyspira murdochii Stanton et al. 1992 is a non-pathogenic host-associated spirochete of the family Brachyspiraceae. Initially isolated from the intestinal content of a healthy swine, the 'group B spirochaetes' were first described under as Serpulina murdochii. Members of the family Brachyspiraceae are of great phylogenetic interest because of the extremely isolated location of this family within the phylum 'Spirochaetes'. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first completed genome sequence of a type strain of a member of the family Brachyspiraceae and only the second genome sequence from a member of the genus Brachyspira. The 3,241,804 bp long genome with its 2,893 protein-coding and 40 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

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