Journal
CHINESE JOURNAL OF CANCER
Volume 34, Issue 1, Pages 50-55Publisher
SUN YAT SEN UNIV MED SCI WHO
DOI: 10.5732/cjc.014.10273
Keywords
Ovarian tumors; classification; molecular abnormalities
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Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. We report herein the newly described molecular abnormalities in epithelial ovarian cancers (carcinomas). Immunohistochemistry and molecular testing help pathologists to decipher the significant heterogeneity of this disease. Our better understanding of the molecular basis of ovarian carcinomas represents the first step in the development of targeted therapies in the near future.
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