1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts α-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism

Herein we provide experimental proof that 1-oxo-2,2,6,6-tetramethylpiperidinium bromide converts alpha-H N, N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism. The reactions reported are rapid, proceed under mild conditions, and afford nitrones in excellent yields.