Related references
Note: Only part of the references are listed.Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9
Giulia Palermo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)
Refining strategies to translate genome editing to the clinic
Tatjana I. Cornu et al.
NATURE MEDICINE (2017)
CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations
Giulia Palermo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
Yavuz S. Dagdas et al.
SCIENCE ADVANCES (2017)
Rationally engineered Cas9 nucleases with improved specificity
Ian M. Slaymaker et al.
SCIENCE (2016)
Structure and Engineering of Francisella novicida Cas9
Hisato Hirano et al.
CELL (2016)
Insights into the Inhibitory Mechanism of D13-9001 to the Multidrug Transporter AcrB through Molecular Dynamics Simulations
Zhicheng Zuo et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2016)
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
Benjamin P. Kleinstiver et al.
NATURE (2016)
Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases
Shengdar Q. Tsai et al.
NATURE REVIEWS GENETICS (2016)
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
Fuguo Jiang et al.
SCIENCE (2016)
Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations
Giulia Palermo et al.
ACS CENTRAL SCIENCE (2016)
Cas9-catalyzed DNA Cleavage Generates Staggered Ends: Evidence from Molecular Dynamics Simulations
Zhicheng Zuo et al.
SCIENTIFIC REPORTS (2016)
Crystal Structure of Staphylococcus aureus Cas9
Hiroshi Nishimasu et al.
CELL (2015)
Systematic Parameterization of Monovalent Ions Employing the Nonbonded Model
Pengfei Li et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Gaussian Accelerated Molecular Dynamics: Unconstrained Enhanced Sampling and Free Energy Calculation
Yinglong Miao et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Comparison of Structural, Thermodynamic, Kinetic and Mass Transport Properties of Mg2+ Ion Models Commonly used in Biomolecular Simulations
Maria T. Panteva et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2015)
Conformational control of DNA target cleavage by CRISPR-Cas9
Samuel H. Sternberg et al.
NATURE (2015)
A Cas9-guide RNA complex preorganized for target DNA recognition
Fuguo Jiang et al.
SCIENCE (2015)
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
Hiroshi Nishimasu et al.
CELL (2014)
Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
Carolin Anders et al.
NATURE (2014)
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
Samuel H. Sternberg et al.
NATURE (2014)
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
Martin Jinek et al.
SCIENCE (2014)
Rational Design of Particle Mesh Ewald Compatible Lennard-Jones Parameters for +2 Metal Cations in Explicit Solvent
Pengfei Li et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
BIOTECHNOLOGY Rewriting a genome
Emmanuelle Charpentier et al.
NATURE (2013)
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
SCIENCE (2013)
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong et al.
SCIENCE (2013)
An overview of the Amber biomolecular simulation package
Romelia Salomon-Ferrer et al.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2013)
Routine Access to Millisecond Time Scale Events with Accelerated Molecular Dynamics
Levi C. T. Pierce et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
Giedrius Gasiunas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jinek et al.
SCIENCE (2012)
Nucleases: diversity of structure, function and mechanism
Wei Yang
QUARTERLY REVIEWS OF BIOPHYSICS (2011)
Large-Scale Conformational Changes of Trypanosoma cruzi Proline Racemase Predicted by Accelerated Molecular Dynamics Simulation
Cesar Augusto F. de Oliveira et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
An equivalent metal ion in one- and two-metal-ion catalysis
Wei Yang
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Crystal structure of T4 endonuclease VII resolving a Holliday junction
Christian Biertuempfel et al.
NATURE (2007)
Making and breaking nucleic acids:: Two-Mg2+-ion catalysis and substrate specificity
W Yang et al.
MOLECULAR CELL (2006)
Scalable molecular dynamics with NAMD
JC Phillips et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
H++:: a server for estimating pKas and adding missing hydrogens to macromolecules
JC Gordon et al.
NUCLEIC ACIDS RESEARCH (2005)
Accelerated molecular dynamics: A promising and efficient simulation method for biomolecules
D Hamelberg et al.
JOURNAL OF CHEMICAL PHYSICS (2004)