Related references
Note: Only part of the references are listed.Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance
Youngtae Jeong et al.
CANCER DISCOVERY (2017)
Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Cytotoxic Effects in Hepatocellular Carcinoma Cells
Subbroto Kumar Saha et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Mechanism of the Antitumor and Radiosensitizing Effects of a Manganese Porphyrin, MnHex-2-PyP
Sung-Won Shin et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in non-small cell lung cancer cells
Qiuyue Zhao et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2016)
Downregulation of Nrf2 by the combination of TRAIL and Valproic acid induces apoptotic cell death of TRAIL-resistant papillary thyroid cancer cells via suppression of Bcl-xL
Hyun-Young Cha et al.
CANCER LETTERS (2016)
Valproic acid, compared to other antiepileptic drugs, is associated with improved overall and progression-free survival in glioblastoma but worse outcome in grade II/III gliomas treated with temozolomide
Navid Redjal et al.
JOURNAL OF NEURO-ONCOLOGY (2016)
The clinical utilization of radiation therapy in Korea between 2009 and 2013
Jin-Kyu Kang et al.
RADIATION ONCOLOGY JOURNAL (2016)
Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway
Alessandra Leone et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Genetic Landscape and Biomarkers of Hepatocellular Carcinoma
Jessica Zucman-Rossi et al.
GASTROENTEROLOGY (2015)
A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma
Andra V. Krauze et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2015)
Lung Cancer Cell Line Screen Links Fanconi Anemia/BRCA Pathway Defects to Increased Relative Biological Effectiveness of Proton Radiation
Qi Liu et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2015)
Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience
Tadashi Kamada et al.
LANCET ONCOLOGY (2015)
Inhibitory effects of valproic acid in DNA double-strand break repair after irradiation in esophageal squamous carcinoma cells
Naoki Makita et al.
ONCOLOGY REPORTS (2015)
Antiepileptic drug use improves overall survival in breast cancer patients with brain metastases in the setting of whole brain radiotherapy
Jay P. Reddy et al.
RADIOTHERAPY AND ONCOLOGY (2015)
Differential DNA repair pathway choice in cancer cells after proton- and photon-irradiation
Andrea O. Fontana et al.
RADIOTHERAPY AND ONCOLOGY (2015)
Valproic acid promotes radiosensitization in meningioma stemlike cells
Hsin-Ying Clair Chiou et al.
ONCOTARGET (2015)
Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells
Dinesh Thotala et al.
ONCOTARGET (2015)
Proton beam radiation induces DNA damage and cell apoptosis in glioma stem cells through reactive oxygen species
R. Alan Mitteer et al.
SCIENTIFIC REPORTS (2015)
In Vitro and In Vivo Radiosensitizing Effect of Valproic Acid on Fractionated Irradiation
Eui Kyu Chie et al.
CANCER RESEARCH AND TREATMENT (2015)
The first private-hospital based proton therapy center in Korea; status of the Proton Therapy Center at Samsung Medical Center
Kwangzoo Chung et al.
RADIATION ONCOLOGY JOURNAL (2015)
Differential response of DU145 and PD prostate cancer cells to ionizing radiation: Role of reactive oxygen species, GSH and Nrf2 in radiosensitivity
Sundarraj Jayakumar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Valproic acid suppresses Nrf2/Keap1 dependent antioxidant protection through induction of endoplasmic reticulum stress and Keap1 promoter DNA demethylation in human lens epithelial cells
Periyasamy Palsamy et al.
EXPERIMENTAL EYE RESEARCH (2014)
Role of Nrf2 activation and NF-κB inhibition in valproic acid induced hepatotoxicity and in diammonium glycyrrhizinate induced protection in mice
Jing Jin et al.
FOOD AND CHEMICAL TOXICOLOGY (2014)
A Phase 1/2 and Biomarker Study of Preoperative Short Course Chemoradiation With Proton Beam Therapy and Capecitabine Followed By Early Surgery for Resectable Pancreatic Ductal Adenocarcinoma
Theodore S. Hong et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2014)
Deficiency in Homologous Recombination Renders Mammalian Cells More Sensitive to Proton Versus Photon Irradiation
Nicole Grosse et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2014)
New and emerging HDAC inhibitors for cancer treatment
Alison C. West et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Temozolomide and irradiation combined treatment-induced Nrf2 activation increases chemoradiation sensitivity in human glioblastoma cells
Zi-Xiang Cong et al.
JOURNAL OF NEURO-ONCOLOGY (2014)
High-dose concurrent chemo-proton therapy for Stage III NSCLC: preliminary results of a Phase II study
Yoshiko Oshiro et al.
JOURNAL OF RADIATION RESEARCH (2014)
Exploration of liver cancer genomes
Tatsuhiro Shibata et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2014)
Relative biological effectiveness (RBE) values for proton beam therapy. Variations as a function of biological endpoint, dose, and linear energy transfer
Harald Paganetti
PHYSICS IN MEDICINE AND BIOLOGY (2014)
Histone deacetylase inhibitor, valproic acid, radiosensitizes the C6 glioma cell line in vitro
Yong Zhou et al.
ONCOLOGY LETTERS (2014)
A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance
Fabio Santoro et al.
BLOOD (2013)
Histone deacetylase inhibitors as radiosensitisers: effects on DNA damage signalling and repair
B. Groselj et al.
BRITISH JOURNAL OF CANCER (2013)
Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Mohamed E. Abazeed et al.
CANCER RESEARCH (2013)
Circadian variation of Valproic acid pharmacokinetics in mice
Wafa Ben-Cherif et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Valproic Acid Use During Radiation Therapy for Glioblastoma Associated With Improved Survival
Christopher A. Barker et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)
Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress
Nicolas Mercado et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
FIRST EVALUATION OF THE BIOLOGIC EFFECTIVENESS FACTORS OF BORON NEUTRON CAPTURE THERAPY (BNCT) IN A HUMAN COLON CARCINOMA CELL LINE
Maria Alejandra Dagrosa et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
Gain of Nrf2 Function in Non-Small-Cell Lung Cancer Cells Confers Radioresistance
Anju Singh et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate
Yumin Hu et al.
BLOOD (2010)
ENHANCEMENT OF RADIATION RESPONSE IN OSTEOSARCOMA AND RHABOMYOSARCOMA CELL LINES BY HISTONE DEACETYLASE INHIBITION
Claudia Blattmann et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2010)
Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth
Ping Zhang et al.
MOLECULAR CANCER THERAPEUTICS (2010)
Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study
Anne Hansen Ree et al.
LANCET ONCOLOGY (2010)
Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
Julia M. Wagner et al.
Clinical Epigenetics (2010)
HDAC Inhibitor, Valproic Acid, Induces p53-Dependent Radiosensitization of Colon Cancer Cells
Xufeng Chen et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2009)
Histone Deacetylase Inhibitors in Cancer Therapy
Andrew A. Lane et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Evaluation of beam wobbling methods for heavy-ion radiotherapy
Shunsuke Yonai et al.
MEDICAL PHYSICS (2008)
Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of γ-H2AX foci
Anupama Munshi et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Valproic acid-induced gene expression through production of reactive oxygen species
Yumiko Kawai et al.
CANCER RESEARCH (2006)
Histone deacetylase 3 (HDAC3) and other class IHDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
AJ Wilson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Valproic acid increases conservative homologous recombination frequency and reactive oxygen species formation: A potential mechanism for valproic acid-induced neural tube defects
EN Defoort et al.
MOLECULAR PHARMACOLOGY (2006)
Cellular and molecular effects of protons: Apoptosis induction and potential implications for cancer therapy
C Di Pietro et al.
APOPTOSIS (2006)
Acetylation and deacetylation of non-histone proteins
MA Glozak et al.
GENE (2005)
Modulation of radiation response by histone deacetylase inhibition
P Chinnaiyan et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species
M Rahmani et al.
CANCER RESEARCH (2005)
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
AA Ruefli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The human histone deacetylase family
SG Gray et al.
EXPERIMENTAL CELL RESEARCH (2001)
The language of covalent histone modifications
BD Strahl et al.
NATURE (2000)