Related references
Note: Only part of the references are listed.Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia
Gero Knittel et al.
NATURE COMMUNICATIONS (2017)
Susceptibility of ATM-deficient pancreatic cancer cells to radiation
Michael Ayars et al.
CELL CYCLE (2017)
ATM Deficiency Is Associated with Sensitivity to PARP1-and ATR Inhibitors in Lung Adenocarcinoma
Anna Schmitt et al.
CANCER RESEARCH (2017)
Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer
Nicholas J. Roberts et al.
CANCER DISCOVERY (2016)
ATM Mutations in Cancer: Therapeutic Implications
Michael Choi et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Genomic analyses identify molecular subtypes of pancreatic cancer
Peter Bailey et al.
NATURE (2016)
Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation
Yiannis Drosos et al.
NEOPLASIA (2016)
A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas
Olca Basturk et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2015)
DNA Replication Stress as a Hallmark of Cancer
Morgane Macheret et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 (2015)
Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis
C. J. Harbort et al.
BLOOD (2015)
Prevalence of Germline Mutations in Cancer Predisposition Genes in Patients With Pancreatic Cancer
Robert C. Grant et al.
GASTROENTEROLOGY (2015)
Whole genomes redefine the mutational landscape of pancreatic cancer
Nicola Waddell et al.
NATURE (2015)
Cellular senescence in aging and age-related disease: from mechanisms to therapy
Bennett G. Childs et al.
NATURE MEDICINE (2015)
Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition
Ronan Russell et al.
NATURE COMMUNICATIONS (2015)
Inflammation-Induced Cell Proliferation Potentiates DNA Damage-Induced Mutations In Vivo
Orsolya Kiraly et al.
PLOS GENETICS (2015)
Having Pancreatic Cancer with Tumoral Loss of ATM and Normal TP53 Protein Expression Is Associated with a Poorer Prognosis
Haeryoung Kim et al.
CLINICAL CANCER RESEARCH (2014)
Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction
Chanjuan Shi et al.
LABORATORY INVESTIGATION (2014)
APPL proteins modulate DNA repair and radiation survival of pancreatic carcinoma cells by regulating ATM
J. Hennig et al.
CELL DEATH & DISEASE (2014)
ATM Mediates pRB Function To Control DNMT1 Protein Stability and DNA Methylation
Awad Shamma et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
Yosef Shiloh et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
ATM and the Molecular Pathogenesis of Ataxia Telangiectasia
Peter J. McKinnon
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)
Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
Janel L. Kopp et al.
CANCER CELL (2012)
Dynamic distribution of claudin proteins in pancreatic epithelia undergoing morphogenesis or neoplastic transformation
Joby J. Westmoreland et al.
DEVELOPMENTAL DYNAMICS (2012)
ATR maintains select progenitors during nervous system development
Youngsoo Lee et al.
EMBO JOURNAL (2012)
Mucin (Muc) expression during pancreatic cancer progression in spontaneous mouse model: potential implications for diagnosis and therapy
Satyanarayana Rachagani et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2012)
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
Andrew V. Biankin et al.
NATURE (2012)
Familial pancreatic cancer-current knowledge
Detlef K. Bartsch et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2012)
ATM Mutations in Patients with Hereditary Pancreatic Cancer
Nicholas J. Roberts et al.
CANCER DISCOVERY (2012)
Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy
Eric A. Collisson et al.
NATURE MEDICINE (2011)
Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas
Massimo Squatrito et al.
CANCER CELL (2010)
The DNA Damage Response: Making It Safe to Play with Knives
Alberto Ciccia et al.
MOLECULAR CELL (2010)
Genomic instability - an evolving hallmark of cancer
Simona Negrini et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia
Jan-Bart M. Koorstra et al.
MODERN PATHOLOGY (2009)
Limited Role of Murine ATM in Oncogene-Induced Senescence and p53-Dependent Tumor Suppression
Alejo Efeyan et al.
PLOS ONE (2009)
The HINT1 tumor suppressor regulates both γ-H2AX and ATM in response to DNA damage
Haiyang Li et al.
JOURNAL OF CELL BIOLOGY (2008)
An oncogene-induced DNA damage model for cancer development
Thanos D. Halazonetis et al.
SCIENCE (2008)
Acinar cells contribute to the molecular heterogeneity of pancreatic intraepithelial neoplasia
Liqin Zhu et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
Raffaella Di Micco et al.
NATURE (2006)
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-β signaling in cooperation with active Kras expression
Hideaki Ijichi et al.
GENES & DEVELOPMENT (2006)
Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse
N Bardeesy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Clonogenic assay of cells in vitro
Nicolaas A. P. Franken et al.
NATURE PROTOCOLS (2006)
Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani et al.
CANCER CELL (2005)
Successful growth and characterization of mouse pancreatic ductal cells:: Functional properties of the Ki-RASG12V oncogene
FS Schreiber et al.
GASTROENTEROLOGY (2004)
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani et al.
CANCER CELL (2003)
ATM and related protein kinases: Safeguarding genome integrity
Y Shiloh
NATURE REVIEWS CANCER (2003)
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
Y Kawaguchi et al.
NATURE GENETICS (2002)
Share Paper
