Journal
SCIENTIFIC REPORTS
Volume 7, Issue -, Pages -Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41598-017-04693-7
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Funding
- National Natural Science Foundation of China [81502916]
- Zhejiang Provincial Natural Science Foundation of China [LY16H300002]
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We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction. By controlling the use of bases, both 6-aza-chromones 5 and 3-(4-oxo-1,4-dihydroquinoline-3-carbonyl)-4H-pyrano[3,2-c] quinolin-4-ones 6 could be selectively obtained in moderate to good yields.
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