Related references
Note: Only part of the references are listed.Global Cancer Incidence and Mortality Rates and Trends-An Update
Lindsey A. Torre et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2016)
RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway
Zahra Shahsavari et al.
TUMOR BIOLOGY (2016)
Detergent sclerosants at sub-lytic concentrations induce endothelial cell apoptosis through a caspase dependent pathway
Osvaldo Cooley-Andrade et al.
APOPTOSIS (2016)
Enhancement of cisplatin-induced colon cancer cells apoptosis by shikonin, a natural inducer of ROS in vitro and in vivo
Guodong He et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Caspase-independent cell death mediated by apoptosis-inducing factor (AIF) nuclear translocation is involved in ionizing radiation induced HepG2 cell death
Hengwen Sun et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Shikonin Derivative DMAKO-05 Inhibits Akt Signal Activation and Melanoma Proliferation
Yao-yao Yang et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2016)
Cytotoxic effects induced by interferon-ω gene lipofection through ROS generation and mitochondrial membrane potential disruption in feline mammary carcinoma cells
Marcela Solange Villaverde et al.
CYTOKINE (2016)
Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis by inhibiting RIPK1
I-Fang Hsin et al.
HEPATOLOGY (2016)
A novel hypoxia-selective epigenetic agent RRx-001 triggers apoptosis and overcomes drug resistance in multiple myeloma cells
D. S. Das et al.
LEUKEMIA (2016)
Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer
Jian Wu et al.
ONCOTARGET (2016)
Oxidative stress-mediated intrinsic apoptosis in human promyelocytic leukemia HL-60 cells induced by organic arsenicals
Xiao-Yang Fan et al.
SCIENTIFIC REPORTS (2016)
Global Cancer Statistics, 2012
Lindsey A. Torre et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2015)
TIPE2 Mediates the Suppressive Effects of Shikonin on MMP13 in Osteosarcoma Cells
Biyong Deng et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2015)
A novel pyrazolone-based derivative induces apoptosis in human esophageal cells via reactive oxygen species (ROS) generation and caspase-dependent mitochondria-mediated pathway
Jing Zhao et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2015)
The stomach in health and disease
R. H. Hunt et al.
GUT (2015)
Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib
Qiaoli Zhao et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
An Involvement of PI3-K/Akt Activation and Inhibition of AIF Translocation in Neuroprotective Effects of Undecylenic Acid (UDA) Against Pro-Apoptotic Factors-Induced Cell Death in Human Neuroblastoma SH-SY5Y Cells
Danuta Jantas et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
Protection of Insects against Viral Infection by Apoptosis-Dependent Phagocytosis
Firzan Nainu et al.
JOURNAL OF IMMUNOLOGY (2015)
Shikonin inhibits the cell viability, adhesion, invasion and migration of the human gastric cancer cell line MGC-803 via the Toll-like receptor 2/nuclear factor-kappa B pathway
Ji Ping Liu et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2015)
Shikonin induces apoptosis in the human gastric cancer cells HGC-27 through mitochondria-mediated pathway
Yue Hou et al.
PHARMACOGNOSY MAGAZINE (2015)
Inhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells
Qiaoli Zhao et al.
ONCOTARGET (2015)
A reactive oxygen species activation mechanism contributes to JS-K-induced apoptosis in human bladder cancer cells
Mingning Qiu et al.
SCIENTIFIC REPORTS (2015)
Regional Arterial Infusion Chemotherapy improves the Pathological Response rate for advanced gastric cancer with Short-term Neoadjuvant Chemotherapy
Zhen-Feng Wu et al.
SCIENTIFIC REPORTS (2015)
Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways
Maryam Zahedifard et al.
SCIENTIFIC REPORTS (2015)
RIP1-dependent Bid cleavage mediates TNFα-induced but Caspase-3-independent cell death in L929 fibroblastoma cells
Guozhu Chen et al.
APOPTOSIS (2015)
Perioperative chemotherapy more of a benefit for overall survival than adjuvant chemotherapy for operable gastric cancer: an updated Meta-analysis
Ya'nan Yang et al.
SCIENTIFIC REPORTS (2015)
Zebrafish Noxa promotes mitosis in early embryonic development and regulates apoptosis in subsequent embryogenesis
J-X Zhong et al.
CELL DEATH AND DIFFERENTIATION (2014)
Shikonin time-dependently induced necrosis or apoptosis in gastric cancer cells via generation of reactive oxygen species
Mu-Jang Lee et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2014)
The metabolic enhancer piracetam attenuates mitochondrion-specific endonuclease G translocation and oxidative DNA fragmentation
Sonam Gupta et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Induction of ROS-Dependent Mitochondria-Mediated Intrinsic Apoptosis in MDA-MB-231 Cells by Glycoprotein from Codium decorticatum
Ramar Thangam et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)
Shikonin induces cell cycle arrest in human gastric cancer (AGS) by early growth response 1 (Egr1)-mediated p21 gene expression
Sun-Joong Kim et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Walnuts (Seeds of Juglandis sinensis L.) Protect Human Epidermal Keratinocytes against UVB-Induced Mitochondria-Mediated Apoptosis through Upregulation of ROS Elimination Pathways
G. Park et al.
SKIN PHARMACOLOGY AND PHYSIOLOGY (2014)
Treatment of gastric cancer
Michele Orditura et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Glutathione synthesis
Shelly C. Lu
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2013)
The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis
Zeze Fu et al.
BMC CANCER (2013)
The molecular mechanisms and gene expression profiling for shikonin-induced apoptotic and necroptotic cell death in U937 cells
Jin-Lan Piao et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2013)
Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1
Chuanjiang Huang et al.
PLOS ONE (2013)
Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy
Subash C. Gupta et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Nec-1 Enhances Shikonin-Induced Apoptosis in Leukemia Cells by Inhibition of RIP-1 and ERK1/2
Weidong Han et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2012)
Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition
Li Lu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma
Ke Gong et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Molecular mechanisms of necroptosis: an ordered cellular explosion
Peter Vandenabeele et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis
Weidong Han et al.
APOPTOSIS (2009)
Shikonin, an ingredient of Lithospermum erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells
Zhang Yi et al.
CANCER LETTERS (2009)
In vivo CD44-CD49d complex formation in autoimmune disease has consequences on T cell activation and apoptosis resistance
Rachid Marhaba et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
The emerging role of reactive oxygen species in cancer therapy
MF Renschler
EUROPEAN JOURNAL OF CANCER (2004)
Lactoperoxidase and hydrogen peroxide metabolism in the airway
GE Conner et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)
Cellular pharmacology studies of shikonin derivatives
X Chen et al.
PHYTOTHERAPY RESEARCH (2002)