Related references
Note: Only part of the references are listed.Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target Enzyme CYP51 from Trypanosoma cruzi
William J. Hoekstra et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase
Alia A. Sagatova et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
First Description of Azole-Resistant Aspergillus fumigatus Due to TR46/Y121F/T289A Mutation in France
Rose-Anne Lavergne et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models
Lisa F. Shubitz et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
In Vitro Biochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatus
Andrew G. S. Warrilow et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Isavuconazonium: First Global Approval
Paul L. McCormack
DRUGS (2015)
Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs
Tatiana Y. Hargrove et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Azole fungicides-understanding resistance mechanisms in agricultural fungal pathogens
Claire L. Price et al.
PEST MANAGEMENT SCIENCE (2015)
Small-angle scattering determination of the shape and localization of human cytochrome P450 embedded in a phospholipid nanodisc environment
Nicholas Skar-Gislinge et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2015)
Contribution of Clinically Derived Mutations in ERG11 to Azole Resistance in Candida albicans
Stephanie A. Flowers et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
The Clinical Candidate VT-1161 Is a Highly Potent Inhibitor of Candida albicans CYP51 but Fails To Bind the Human Enzyme
A. G. S. Warrilow et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2014)
Azole-resistant Aspergillus fumigatus with the environmental TR46/Y121F/T289A mutation in India
Anuradha Chowdhary et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)
Aspergillus fumigatus harbouring the sole Y121F mutation shows decreased susceptibility to voriconazole but maintained susceptibility to itraconazole and posaconazole
J. Lescar et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)
Multi-azole-resistant Aspergillus fumigatus in the environment in Tanzania
Anuradha Chowdhary et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)
Sensitivity of Phakopsora pachyrhizi towards quinone-outside-inhibitors and demethylation-inhibitors, and corresponding resistance mechanisms
Helena K. Schmitz et al.
PEST MANAGEMENT SCIENCE (2014)
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer
Brian C. Monk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Prothioconazole and Prothioconazole-Desthio Activities against Candida albicans Sterol 14-α-Demethylase
Josie E. Parker et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2013)
Aspergillosis due to Voriconazole Highly Resistant Aspergillus fumigatus and Recovery of Genetically Related Resistant Isolates From Domiciles
Jan W. M. van der Linden et al.
CLINICAL INFECTIOUS DISEASES (2013)
Update on mechanisms of azole resistance in Mycosphaerella graminicola and implications for future control
Hans J. Cools et al.
PEST MANAGEMENT SCIENCE (2013)
Identification of a Cryptococcus neoformans Cytochrome P450 Lanosterol 14α-Demethylase (Erg11) Residue Critical for Differential Susceptibility between Fluconazole/Voriconazole and Itraconazole/Posaconazole
Edward Sionov et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Correlation between Triazole Treatment History and Susceptibility in Clinically Isolated Aspergillus fumigatus
Masato Tashiro et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Triazole Fungicides Can Induce Cross-Resistance to Medical Triazoles in Aspergillus fumigatus
Eveline Snelders et al.
PLOS ONE (2012)
Tackling Human Fungal Infections
Gordon D. Brown et al.
SCIENCE (2012)
iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM
T. Geoff G. Battye et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2011)
Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans
Hyoung-Goo Park et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
Multiple mechanisms account for resistance to sterol 14 alpha-demethylation inhibitors in field isolates of Mycosphaerella graminicola
Pierre Leroux et al.
PEST MANAGEMENT SCIENCE (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51)
Andrew G. S. Warrilow et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Epidemiology of Opportunistic Fungal Infections in Latin America
Marcio Nucci et al.
CLINICAL INFECTIOUS DISEASES (2010)
Epidemiology of Invasive Mycoses in North America
Michael A. Pfaller et al.
CRITICAL REVIEWS IN MICROBIOLOGY (2010)
Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-Year Analysis of Susceptibilities of Candida Species to Fluconazole and Voriconazole as Determined by CLSI Standardized Disk Diffusion
M. A. Pfaller et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2010)
Structural Basis of Human CYP51 Inhibition by Antifungal Azoles
Natallia Strushkevich et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
Benjamin J. Park et al.
AIDS (2009)
Measurement of cytochrome P450 and NADPH-cytochrome P450 reductase
F. Peter Guengerich et al.
NATURE PROTOCOLS (2009)
Frequency and Evolution of Azole Resistance in Aspergillus fumigatus Associated with Treatment Failure
Susan J. Howard et al.
EMERGING INFECTIOUS DISEASES (2009)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiaev
Erwin Lamping et al.
EUKARYOTIC CELL (2007)
Epidemiology of invasive candidiasis: a persistent public health problem
M. A. Pfaller et al.
CLINICAL MICROBIOLOGY REVIEWS (2007)
Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole
LJ Wheat et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2006)
Scaling and assessment of data quality
P Evans
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
Thermodynamic consequences of disruptiner a water-mediated hydrogen bond network in a protein: pheromone complex
SD Sharrow et al.
PROTEIN SCIENCE (2005)
Incidence of invasive aspergillosis following hematopoietic stem cell and solid organ transplantation: interim results of a prospective multicenter surveillance program
J Morgan et al.
MEDICAL MYCOLOGY (2005)
The Cambridge Structural Database: a quarter of a million crystal structures and rising
FH Allen
ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE (2002)
Crystal structure of cytochrome P450 14α-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors
LM Podust et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Genetic analysis of azole resistance in the Darlington strain of Candida albicans
H Kakeya et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)
Share Paper
