4.7 Article

Stearoyl-CoA desaturase inhibition blocks formation of hepatitis C virus-induced specialized membranes

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

Hepatitis C Virus Induced Up-Regulation of MicroRNA-27: A Novel Mechanism for Hepatic Steatosis

Ragunath Singaravelu et al.

HEPATOLOGY (2014)

Article Biochemistry & Molecular Biology

Modulation of Fatty Acid Synthase Enzyme Activity and Expression during Hepatitis C Virus Replication

Neda Nasheri et al.

CHEMISTRY & BIOLOGY (2013)

Article Chemistry, Medicinal

Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series

Nicolas Lachance et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Article Biochemical Research Methods

NIH Image to ImageJ: 25 years of image analysis

Caroline A. Schneider et al.

NATURE METHODS (2012)

Article Chemistry, Medicinal

Nicotinic acids: Liver-targeted SCD inhibitors with preclinical anti-diabetic efficacy

David A. Powell et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)

Review Infectious Diseases

Evolving epidemiology of hepatitis C virus

D. Lavanchy

CLINICAL MICROBIOLOGY AND INFECTION (2011)

Review Biochemistry & Molecular Biology

Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy

John Paul Pezacki et al.

NATURE CHEMICAL BIOLOGY (2011)

Review Biochemistry & Molecular Biology

Hepatitis c virus and host cell lipids An intimate connection

Gualtiero Alvisi et al.

RNA BIOLOGY (2011)

Review Endocrinology & Metabolism

Unique ties between hepatitis C virus replication and intracellular lipids

Eva Herker et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2011)

Article Biochemistry & Molecular Biology

Dynamics of lipid droplets induced by the hepatitis C virus core protein

Rodney K. Lyn et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Chemistry, Medicinal

Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438)

Serge Leger et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Article Chemistry, Medicinal

SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors

Yeeman K. Ramtohul et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Review Biochemistry & Molecular Biology

Host-virus interactions during hepatitis C virus infection: a complex and dynamic molecular biosystem

John Paul Pezacki et al.

MOLECULAR BIOSYSTEMS (2010)

Article Multidisciplinary Sciences

Membrane-shaping host reticulon proteins play crucial roles in viral RNA replication compartment formation and function

Arturo Diaz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Endocrinology & Metabolism

Biochemical and physiological function of stearoyl-CoA desaturase

Chad M. Paton et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)

Review Cell Biology

Coordination of Lipid Metabolism in Membrane Biogenesis

Axel Nohturfft et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice

Herve Lerat et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Virology

A Dynamic View of Hepatitis C Virus Replication Complexes

Benno Woelk et al.

JOURNAL OF VIROLOGY (2008)

Review Microbiology

Modification of intracellular membrane structures for virus replication

Sven Miller et al.

NATURE REVIEWS MICROBIOLOGY (2008)

Review Cell Biology

Membrane lipids: where they are and how they behave

Gerrit van Meer et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Multidisciplinary Sciences

Advantages of a single-crystal production assay to study cell culture-adaptive mutations of hepatitis C virus

Rodney S. Russell et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

The influence of fatty acids on model cholesterol/phospholipid membranes

Katarzyna Hac-Wydro et al.

CHEMISTRY AND PHYSICS OF LIPIDS (2007)

Article Cell Biology

The lipid droplet is an important organelle for hepatitis C virus production

Yusuke Miyanari et al.

NATURE CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

HCV core protein induces hepatic lipid accumulation by activating SREBP1 and PPARγ

Kook Hwan Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Review Cell Biology

Lipid droplets: a unified view of a dynamic organelle

S Martin et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Host sphingolipid biosynthesis as a target for hepatitis C virus therapy

H Sakamoto et al.

NATURE CHEMICAL BIOLOGY (2005)

Review Cell Biology

Wrapping things up about virus RNA replication

J Mackenzie

TRAFFIC (2005)

Article Gastroenterology & Hepatology

Hepatitis C virus core protein modulates fatty acid metabolism and thereby causes lipid accumulation in the liver

A Yamaguchi et al.

DIGESTIVE DISEASES AND SCIENCES (2005)

Article Biochemistry & Molecular Biology

Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication

Y Miyanari et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemical Research Methods

A replicon-based bioassay for the measurement of interferons in patients with chronic hepatitis C

JM Vrolijk et al.

JOURNAL OF VIROLOGICAL METHODS (2003)

Article Biochemistry & Molecular Biology

Inhibition of hepatitis C virus RNA replication by 2′-modified nucleoside analogs

SS Carroll et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

Genomic analysis of the host response to hepatitis C virus infection

AI Su et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Cell Biology

Vaccinia virus DNA replication occurs in endoplasmic reticulum-enclosed cytoplasmic mini-nuclei

N Tolonen et al.

MOLECULAR BIOLOGY OF THE CELL (2001)