Related references
Note: Only part of the references are listed.Inhibition of apical sodium-dependent bile acid transporter as a novel treatment for diabetes
Lihong Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Molecular mechanisms underlying bile acid-stimulated glucagon-like peptide-1 secretion
H. E. Parker et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: a randomised controlled study
C. Beysen et al.
DIABETOLOGIA (2012)
TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading
Thijs W. H. Pols et al.
CELL METABOLISM (2011)
Bile Acid Metabolism and the Pathogenesis of Type 2 Diabetes
Janne Prawitt et al.
CURRENT DIABETES REPORTS (2011)
Bile Acid Sequestrants Improve Glycemic Control in Type 2 Diabetes: A Proposed Mechanism Implicating Glucagon-Like Peptide 1 Release
Alan F. Hofmann
HEPATOLOGY (2011)
The G-Protein-Coupled Bile Acid Receptor, Gpbar1 (TGR5), Negatively Regulates Hepatic Inflammatory Response Through Antagonizing Nuclear Factor Kappa Light-Chain Enhancer of Activated B Cells (NF-κB) in Mice
Yan-Dong Wang et al.
HEPATOLOGY (2011)
Weight Beneficial Treatments for Type 2 Diabetes
L. F. Meneghini et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2011)
The G Protein-Coupled Bile Acid Receptor, TGR5, Stimulates Gallbladder Filling
Tingting Li et al.
MOLECULAR ENDOCRINOLOGY (2011)
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1
Quan Shang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Bile Acids as Regulators of Hepatic Lipid and Glucose Metabolism
Michael Trauner et al.
DIGESTIVE DISEASES (2010)
EFFECTS OF COLESEVELAM, ROSIGLITAZONE, OR SITAGLIPTIN ON GLYCEMIC CONTROL AND LIPID PROFILE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS INADEQUATELY CONTROLLED BY METFORMIN MONOTHERAPY
Scott. P. Rigby et al.
ENDOCRINE PRACTICE (2010)
Bile Salt Sequestration Induces Hepatic De Novo Lipogenesis Through Farnesoid X Receptor- and Liver X Receptorα-Controlled Metabolic Pathways in Mice
Hilde Herrema et al.
HEPATOLOGY (2010)
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system
D. P. Poole et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
Cholestyramine Reverses Hyperglycemia and Enhances Glucose-Stimulated Glucagon-Like Peptide 1 Release in Zucker Diabetic Fatty Rats
Lihong Chen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis
Charles Thomas et al.
CELL METABOLISM (2009)
Rationale and design of a clinical trial to evaluate metformin and colesevelam HCl as first-line therapy in type 2 diabetes and colesevelam HCl in prediabetes
Michael R. Jones et al.
CURRENT MEDICAL RESEARCH AND OPINION (2009)
The Membrane-Bound Bile Acid Receptor TGR5 Is Localized in the Epithelium of Human Gallbladders
Verena Keitel et al.
HEPATOLOGY (2009)
Bile acids as regulatory molecules
Phillip B. Hylemon et al.
JOURNAL OF LIPID RESEARCH (2009)
Discovery of 6α-Ethyl-23(S)-methylcholic Acid (S-EMCA, INT-777) as a Potent and Selective Agonist for the TGR5 Receptor, a Novel Target for Diabesity
Roberto Pellicciari et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Expression and function of the bile acid receptor TGR5 in Kupffer cells
Verena Keitel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Modulating LDL cholesterol and glucose in patients with type 2 diabetes mellitus: targeting the bile acid pathway
Allison B. Goldfine
CURRENT OPINION IN CARDIOLOGY (2008)
Colesevelam HCl improves glycemic control and reduces LDL cholesterol in patients with inadequately controlled type 2 diabetes on sulfonylurea-based therapy
Vivian A. Fonseca et al.
DIABETES CARE (2008)
Interrupting bile-acid handling and lipid and glucose control: Effects of colesevelam on glucose levels
Michael H. Davidson
JOURNAL OF CLINICAL LIPIDOLOGY (2008)
Novel potent and selective bile acid derivatives as TGR5 agonists: Biological screening, structure-activity relationships, and molecular modeling studies
Hiroyuki Sato et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Targeting bile-acid signalling for metabolic diseases
Charles Thomas et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Endocrine and paracrine role of bile acids
Verena Keitel et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2008)
The physiology of glucagon-like peptide 1
Jens Juul Holst
PHYSIOLOGICAL REVIEWS (2007)
Rationale and design of a prospective clinical trial program to evaluate the glucose-lowering effects of colesevelam HCl in patients with type 2 diabetes mellitus
Harold E. Bays et al.
CURRENT MEDICAL RESEARCH AND OPINION (2007)
Results of the Glucose-Lowering Effect of WelChol Study (GLOWS): A randomized, double-blind, placebo-controlled pilot study evaluating the effect of colesevelam hydrochloride on glycemic control in subjects with type 2 diabetes
Franklin J. Zieve et al.
CLINICAL THERAPEUTICS (2007)
Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin
Misato Kobayashi et al.
DIABETES (2007)
Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice
Takaharu Maruyama et al.
JOURNAL OF ENDOCRINOLOGY (2006)
Effects of intravenous glucagon-like peptide-1 on gastric emptying and intragastric distribution in healthy subjects: Relationships with postprandial glycemic and insulinemic responses
TJ Little et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
M Watanabe et al.
NATURE (2006)
Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats
PK Chelikani et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)
Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1
S Katsuma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Protein hydrolysates stimulate proglucagon gene transcription in intestinal endocrine cells via two elements related to cyclic AMP response element
JC Gevrey et al.
DIABETOLOGIA (2004)
A G protein-coupled receptor responsive to bile acids
Y Kawamata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Identification of membrane-type receptor for bile acids (M-BAR)
T Maruyama et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)