4.2 Article

Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms

Related references

Note: Only part of the references are listed.
Article Chemistry, Medicinal

Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase

Peter S. Dragovich et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Article Biochemical Research Methods

Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase

Sally Dempster et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2014)

Article Chemistry, Medicinal

Identification of 2-amino-5-aryl-pyrazines as inhibitors of human lactate dehydrogenase

Benjamin P. Fauber et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Article Chemistry, Medicinal

Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase

Peter S. Dragovich et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Article Chemistry, Medicinal

Fragment Growing and Linking Lead to Novel Nanomolar Lactate Dehydrogenase Inhibitors

Anna Kohlmann et al.

JOURNAL OF MEDICINAL CHEMISTRY (2013)

Article Chemistry, Medicinal

Galloflavin (CAS 568-80-9): A Novel Inhibitor of Lactate Dehydrogenase

Marcella Manerba et al.

CHEMMEDCHEM (2012)

Review Immunology

Targeting glucose metabolism for cancer therapy

Robert B. Hamanaka et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

Article Chemistry, Medicinal

Design and Synthesis of Novel Lactate Dehydrogenase A Inhibitors by Fragment-Based Lead Generation

Richard A. Ward et al.

JOURNAL OF MEDICINAL CHEMISTRY (2012)

Article Biochemical Research Methods

REFMAC5 for the refinement of macromolecular crystal structures

Garib N. Murshudov et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)

Article Biochemical Research Methods

Overview of the CCP4 suite and current developments

Martyn D. Winn et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)

Article Chemistry, Medicinal

Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5

Carlotta Granchi et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)

Review Biotechnology & Applied Microbiology

Targeting cancer metabolism: a therapeutic window opens

Matthew G. Vander Heiden

NATURE REVIEWS DRUG DISCOVERY (2011)

Article Biochemical Research Methods

MolProbity: all-atom structure validation for macromolecular crystallography

Vincent B. Chen et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Biochemical Research Methods

XDS

Wolfgang Kabsch

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Multidisciplinary Sciences

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

Anne Le et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Chemistry, Physical

Modeling of Isotope Effects on Binding Oxamate to Lactic Dehydrogenase

Katarzyna Swiderek et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2009)

Article Chemistry, Multidisciplinary

Web-Ice:: integrated data collection and analysis for macromolecular crystallography

A. Gonzalez et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2008)

Article Chemistry, Multidisciplinary

Phaser crystallographic software

Airlie J. McCoy et al.

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)

Article Biochemical Research Methods

Coot:: model-building tools for molecular graphics

P Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

A deliberate approach to screening for initial crystallization conditions of biological macromolecules

JR Luft et al.

JOURNAL OF STRUCTURAL BIOLOGY (2003)