4.6 Article

Effect of surface properties in protein corona development on mesoporous silica nanoparticles

Journal

RSC ADVANCES
Volume 4, Issue 55, Pages 29134-29138

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra03277b

Keywords

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Funding

  1. Spanish Ministry of Economy and Competiveness [SEV-2012-0267, MAT2012-39290-C02-02, IPT-2012-0574-300000]
  2. University of Vermont

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The composition of the protein corona formed on mesoporous silica nanoparticles with several surface modifications was characterized. Low MW serum proteins were preferentially adsorbed, and PEGylated nanoparticles did not adsorb protein regardless of PEG chain length.

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