4.6 Article

Fluorescent nitric oxide detection using cobalt substituted myoglobin

Journal

RSC ADVANCES
Volume 4, Issue 20, Pages 10269-10272

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra47658h

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We report two advances in optical biosensing of nitric oxide (NO). Firstly, we developed an improved biomolecular gated system for fluorescent transduction of heme-NO binding. Secondly, through a cobalt substitution, the detection limit for NO was decreased an order of magnitude lower than that of native myoglobin.

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