Journal
RSC ADVANCES
Volume 4, Issue 8, Pages 3659-3667Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra46762g
Keywords
-
Categories
Funding
- Fundacao para a Ciencia e a Tecnologia [PEst-C/EQB/LA0006/2011, PTDC/CTM-NAN/112241/2009]
- COMPETE program, Portugal [PEst-C/EQB/LA0006/2011, PTDC/CTM-NAN/112241/2009]
- Xunta de Galicia (INBIOMED-Feder unha maneira de facer Europa)
- Spanish MINECO [MAT2010-15374]
- FCT [SFRH/BD/28209/2006, SFRH/BPD/84018/2012]
Ask authors/readers for more resources
A novel synthetic methodology for star shaped gold-coated magnetic nanoparticles is reported. The coating is performed in two steps: formation of gold nuclei at the surface of magnetite nanoparticles followed by growth of the gold nuclei into a complete star shaped shell. The star-shaped gold-coated magnetic nanoparticles thus obtained preserve the magnetic properties of the precursor magnetite nanoparticles, e. g. they can be easily separated with a magnet. In addition, the gold coating provides interesting optical properties while simultaneously allowing for biofunctionalization that may be advantageous for biological applications, such as (bio)detection via surface-enhanced Raman spectroscopy (SERS). As a proof-of-concept, a capping agent terminated with a nickel(II)-nitrilotriacetate group showing high affinity for histidine was used to modify the surface of the nanoparticles. The resulting star-shaped nanoparticles were used to selectively capture histidine-tagged maltose-binding protein from a crude cell extract. Finally, the performance of star shaped gold-coated magnetic nanoparticles as SERS platforms was demonstrated through the detection of Raman active dye (Astra Blue).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available