4.6 Article

Enzyme catalytic promiscuity: lipase catalyzed synthesis of substituted 2H-chromenes by a three-component reaction

Journal

RSC ADVANCES
Volume 4, Issue 49, Pages 25633-25636

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra03367a

Keywords

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Funding

  1. National Natural Science Foundation of China [21172093, 31070708, 21072075]
  2. Natural Science Foundation of Jilin Province of China [201115039, 20140101141JC]

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A new method for the synthesis of substituted 2H-chromenes catalyzed by lipase was reported in the first time. Besides providing a simple and efficient method for the synthesis of 2H-chromenes, this study extends the applicability of lipase in organic synthesis.

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