4.6 Article

Highly efficient [3+2] reaction of 3-vinylindoles with 3-indolylmethanols by Bronsted-acid catalysis

Journal

RSC ADVANCES
Volume 4, Issue 14, Pages 6916-6919

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra47056c

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Funding

  1. NSFC [21272002]
  2. Fundamental Research Funds for the Central Universities [XDJK2013B028]
  3. Program for New Century Excellent Talents in Universities [NCET-12-0929]

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This paper describes a highly efficient [3 + 2] reaction between 3-vinylindoles and 3-indolylmethanols. Novel 2,3-bisindolylmethanes were prepared as single diastereoisomers in high yields with the promotion of 1 mol% 2-hydroxy-3,5-dinitrobenzoic acid.

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