4.6 Article

Copper-catalyzed tandem N-arylation/condensation: synthesis of quinazolin-4(3H)-ones from 2-halobenzonitriles and amides

Journal

RSC ADVANCES
Volume 4, Issue 84, Pages 44811-44814

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra08031a

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Funding

  1. International S&T Cooperation Program of China [2012DFR40240]

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A novel, straightforward and practical copper-catalyzed domino protocol for synthesis of quinazolin-4(3H)-one derivatives from commercially available 2-halobenzonitriles and amides was successfully developed.

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