4.6 Article

Fluorogenic sensing of H2S in blood and living cells via reduction of aromatic dialkylamino N-oxide

Journal

RSC ADVANCES
Volume 4, Issue 57, Pages 30398-30401

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra03677h

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Funding

  1. National Basic Research Program of China (973 Program) [2013CB933800]
  2. National Natural Science Foundation of China [21372018]

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A fluorescent chemodosimeter, N-oxide of 7-diethylamino-4-methylcoumarin, was developed for H2S detection based on a new water soluble aromatic dialkylamine N-oxide group and their selectivity and sensitivity for fluorescent detection of H2S were evaluated in aqueous solution and blood media. Fluorescence sensing of H2S was also achieved in MCF-7 cells.

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