Journal
RSC ADVANCES
Volume 4, Issue 92, Pages 50369-50372Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra10880a
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Funding
- National Natural Science Foundation of China [21202067]
- Fundamental Research Funds for the Central Universities [lzujbky-2014-71]
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A metal-free and efficient method for the synthesis of substituted pyridines with aldehydes and NH4OAc under mild conditions using air as the oxidant was developed. This oxidative cyclization process involves direct C-H bond functionalization, C-C/C-N bond formation and C-C bond cleavage.
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