Pillarene functionalized polymer monolithic column for the solid-phase microextraction preconcentration of parabens

Poly(glycidyl methacrylate-co-ethylene dimethacrylate) modified with a new supramolecular macrocycle, carboxylatopillar[5] arene, was successfully prepared inside a capillary. The functionalized polymer monolith material was characterized by scanning electron microscopy, X-ray photoelectron spectroscopy, thermogravimetric analysis, and Fourier-transformed infrared spectra. The experimental results showed that this type of polymer possess a good network skeleton structure and excellent extraction properties for the enrichment of parabens by polymer monolith solid-phase microextraction coupled with high performance liquid chromatography. Compared with other pre-treatment methods, the simple operation and inexpensive instrumentation characteristics of the developed polymer monolith SPME method make it more suitable for the extraction of parabens in red wine samples with great potential for further broadening its applications in the enrichment of other real samples.