4.6 Article

A fluorescent probe for hydrazine and its in vivo applications

Journal

RSC ADVANCES
Volume 4, Issue 79, Pages 41807-41811

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra08101c

Keywords

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Funding

  1. National Natural Science Foundation of China [21206137, 21476185]
  2. Fundamental Research Funds for the Central Universities [2014YB027, 2452013py014]
  3. Shaanxi Province Science and Technology [2014K11-01-02-06]
  4. Scientific Research Foundation of Northwest AF University [Z111021103, Z111021107]

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In aqueous solution, probe 1 selectively reacts with hydrazine (N2H4), leading to a 30.5-fold turn-on fluorescence response at 560 nm. Probe 1 can detect hydrazine in both solution and gas state by color changes from readily prepared strips. Furthermore, it was found that probe 1 is able to detect hydrazine in Hela cells.

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