4.6 Article

Facile synthesis of a reduction-responsive amphiphilic triblock polymer via a selective thiol-disulfide exchange reaction

Journal

RSC ADVANCES
Volume 4, Issue 90, Pages 48897-48900

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra07792j

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A reduction-responsive amphiphilic triblock copolymer mPEG-b-PDS-b-mPEG was synthesized via polycondensation between a dithiol and dipyridyl disulfide, followed by a selective thiol-disulfide exchange reaction. The reduction-triggered release of Nile Red by DTT was further demonstrated using fluorescence spectroscopy.

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