Journal
RSC ADVANCES
Volume 4, Issue 103, Pages 59405-59408Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4ra11713a
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Funding
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Education [2013R1A1A2059458]
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The product profiles of mppF, mppA, and mppC mutants substantiate that MppA-mediated omega-2 ketoreduction is a prerequisite for the synthesis of the pyranoquinone bicyclic core of the Monascus azaphilone pigment and that MppC activity determines the regioselectivity of the spontaneous Knoevenagel condensation.
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