Journal
RSC ADVANCES
Volume 3, Issue 28, Pages 11132-11139Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra23264f
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Funding
- Natural Science Foundation of Fujian Province [2010J06017]
- National Basic Research Program of China [2010CB732203]
- National Natural Science Foundation of China [50973019]
- Research Fund for the Doctoral Program of Higher Education of China [20123503110003]
- Program for New Century Excellent Talents in Fujian Province University [JA10059]
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In mimicking the chemical structure of collagen nanofiber, electrospun polyacrylonitrile nanofibers were hydrolyzed to generate amide and carboxyl groups on the fiber surface. These fibers were applied as templates in bio-mimicking the growth of hydroxyapaptite (HAp). Nucleation and growth of HAp crystals were fast, and bioactive HAp/fiber composites were produced. The composite scaffold was non-cytotoxic to human dental pulp stem cells.
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