An efficient one-pot three-component reaction for the synthesis of novel functionalized pyrano[3,2-c]coumarins catalyzed by Na2CO3 in aqueous medium

An efficient green method for the synthesis of novel functionalized pyrano[3,2-c]coumarins from a one-pot three-component reaction of 4-hydroxycoumarins, dialkylacetylenedicarboxylates and alkyl acetonitriles catalyzed by Na2CO3 in aqueous medium was developed. The pure products were obtained in high yield from a simple work-up procedure.