Journal
RSC ADVANCES
Volume 3, Issue 33, Pages 13626-13629Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra42730g
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Funding
- National Natural Science Foundation of China [21032007, 21172038]
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4-Halo isoquinoline N-oxides could be synthesized efficiently via the electrophilic cyclization of 2-alkynylbenzaldoximes, involving the in situ generation of the halonium ion in water. The one-pot cyclization-Suzuki reaction in an aqueous system afforded the functionalized isoquinoline N-oxides in good yields.
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