4.6 Article

Peptide nucleic acids are an additional class of aptamers

Journal

RSC ADVANCES
Volume 3, Issue 17, Pages 5828-5831

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra40553b

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Funding

  1. Basic Science Program through the National Research Foundation (NRF) of Korea
  2. Ministry of Education, Science and Technology (MEST) [2011-0021956, 2012-001680]
  3. National Research Foundation of Korea [2011-0021956] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Peptide nucleic acids (PNAs) have been known for their similar or superior properties to DNA or RNA since 1991, but not regarded as a separate class of aptamers. We report here an interesting additional property of PNAs revealed by graphene oxide (GO)-based assays, suggesting that nucleobases in certain aptamers play more important roles in strong and selective binding to the target molecules.

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