Kumada-Tamao-Corriu cross-coupling reaction of O-based electrophiles with Grignard reagents via C-O bond activation

Kumada-Tamao-Corriu coupling reaction catalyzed by transition-metal has been widely used in organic synthesis. Organic halides are mostly used as electrophiles in this reaction. Compared with organic halides, O-based electrophiles are less explored. In this review, we summarized the Kumada-Tamao-Corriu coupling reaction of O-based electrophiles, including sulfonates, phosphates, ethers, and carboxylates.