Journal
RSC ADVANCES
Volume 3, Issue 39, Pages 17938-17944Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ra43499k
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This work reports on the influence of polarization and morphology of electroactive poly(vinylidene fluoride), PVDF, on the adhesion and morphology of myoblast cells. Non-poled, poled+ and poled- beta-PVDF films were prepared by solvent casting followed by corona poling. Furthermore, random and aligned electrospun beta-PVDF fiber mats were also prepared. It is demonstrated that negatively charged surfaces improve cell adhesion and proliferation and that the directional growth of the myoblast cells can be achieved by culturing the cell on aligned fibers. Therefore, the potential application of electroactive materials for muscle regeneration is demonstrated.
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