Journal
RSC ADVANCES
Volume 2, Issue 17, Pages 6733-6735Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ra20707a
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Funding
- National Natural Science Foundation of China [20972065, 21074054, 51173078, 21172106]
- National Basic Research Program of China [2010CB923303]
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A highly regioselective sp(3) C-H amination of aryl amides with N-substituted pyrrolidin-2-ones has been developed with a catalyst Fe(II) complex with TBHP as a benign oxidant. This facile method can offer rapid access to the amination reaction of N-substituted pyrrolidin-2-ones in moderate to excellent yields.
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