Room temperature synthesis of isoquino[2,1-a][3,1]oxazine and isoquino[2,1-a]pyrimidine derivatives via visible light photoredox catalysis

A novel and efficient construction of isoquino[2,1-a][3,1]oxazine and isoquino[2,1-a]pyrimidine frameworks has been realized by means of visible light photocatalytic reactions using air as the oxidant at room temperature. This strategy offers a direct and rapid access to two kinds of biologically important fused heterocycles in good to excellent yields.