Journal
RSC ADVANCES
Volume 2, Issue 11, Pages 4636-4638Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ra20307c
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Funding
- National Natural Science Foundation [20975108, 21105066, 21004056]
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For the first time an anti-cocaine aptamer was cut into three fragments, which were still able to specifically assemble with cocaine and render the sensitive and highly selective optical detection of cocaine. The assembly process possesses significantly different thermodynamic signature compared to the interactions involved monolithic aptamer and double-fragment aptamer.
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